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Single-cell RNA sequencing reveals the local cell landscape in mouse epididymal initial segment during aging

ABSTRACT: Introduction: Morphological and functional alternations of the aging reproductive organs result in decreased male fertility. We previously reported that the epididymal initial segment underwent remarkable histological changes and chronic immune-activation in mouse during aging. However, the local cell landscape in the aged epididymal initial segment are poorly understood. Objectives: We aimed to characterize the aging-associated cellular and molecular features of mouse epididymal initial segment.

ORGANISM(S): Mus musculus

PROVIDER: GSE226310 | GEO | 2023/04/23

REPOSITORIES: GEO

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RNA sequencing analysis of busulfan-treated initial segment-caput epididymis.

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Testicular lumicrine factors regulate ERK, STAT and NFKB pathways in the initial segment of the rat epididymis to prevent apoptosis

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Testicular lumicrine factors regulate ERK, STAT and NFKB pathways in the initial segment of the rat epididymis to prevent apoptosis

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