Anti-tumor necrosis factor-alpha monoclonal antibody suppresses colorectal cancer growth in an orthotopic transplant mouse model

ABSTRACT: In order to investigate the effect of anti-TNFα mAb on colorectal cancer, we generated a orthotopic transplantation model of colorecatal cancer. We performed a comprehensive gene expression profiling analysis by extracting total RNA from cecal tumor of mice treated with and without anti-TNFα mAb (MP6-XT22)

ORGANISM(S): Mus musculus

PROVIDER: GSE226619 | GEO | 2023/03/06

REPOSITORIES: GEO