Norepinephrine modulates calcium dynamics in cortical oligodendrocyte precursor cells promoting proliferation during arousal in mice

ABSTRACT: Oligodendrocyte precusor cells (OPCs) exhibit near membrane calcium transients that can be enhacned by norepinephrine-mediated activation of alpha1A adrenergic receptors in vivo. In order to determine if norepinephrine directly modulates OPC behaviors, we performed an unbiased, transcriptomic-based assessment of biological processes altered in OPCs after activation of alpha1 adrenergic receptors

ORGANISM(S): Mus musculus

PROVIDER: GSE226635 | GEO | 2023/06/26

REPOSITORIES: GEO