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Single-cell RNA-sequencing from stroma in a mouse submandibular salivary gland 14 days after ligation or mock surgery

ABSTRACT: The submandibular salivary gland stroma makes up only a small portion of the total salivary gland and the stromal response to salivary gland injury has been understudied. We used single-cell RNA-sequencing (scRNAseq) to analyze which cell types are present in both control and ligated samples, how the cell type abundance is altered following injury, and how the transcriptome of those cells is being altered. This will allow us to examine which cell types are important contributors to fibrosis induced by salivary gland ductal ligation injury.

ORGANISM(S): Mus musculus

PROVIDER: GSE226640 | GEO | 2023/03/29

REPOSITORIES: GEO

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