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Gene expression data from aortic tissues of PPE-AAA mice receiving systemic lenvatinib treatment

ABSTRACT: Abdominal aortic aneurysm (AAA) is a disease with high morbidity and mortality, especially when ruptured. The rationale of this study was to evaluate the repurposing of lenvatinib, a multi–tyrosine kinase inhibitor, in limiting experimental AAA growth targeting vascular smooth muscle cells (VSMCs) and angiogenesis. We applied systemic lenvatinib treatment to porcine pancreatic elastase(PPE)-induced murine aortic aneurysms and profiled their gene expression through Affymetrix MTA1-0 microarray.

ORGANISM(S): Mus musculus

PROVIDER: GSE226736 | GEO | 2023/03/07

REPOSITORIES: GEO

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Mus musculus

Project description:MicroRNA transciptional profiling in murine abdominal aortic aneurysm (AAA), porcine pancreatic elastase (PPE) model - Day 7

| PRJNA221776 | ENA