Transcriptomics

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Transcriptome data from U2OS cells and hTERT CRISPR clones


ABSTRACT: To assess the biological significances of p-hTERT in ALT cells, we used the CRISPR-Cas9 system targeting the hTERT gene and performed RNA-seq to analyze the profile of gene expression in hTERT-CRISPR clones (clone#1 and #2). The subsequent gene ontology (GO) analysis showed enrichment of genes involved in cell cycle process and DNA replication within genes down-regulated in hTERT-CRISPR clones.

ORGANISM(S): Homo sapiens

PROVIDER: GSE226963 | GEO | 2024/04/08

REPOSITORIES: GEO

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