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The role of miR-99a-5p in the immune regulation of host macrophages infected by Mycobacterium tuberculosis

ABSTRACT: This study aims to identify the specific miRNA of mycobacterium tuberculosis (M.tb) infected THP-1 by next-generation sequencing, and further to explore the role of miRNA in innate immunity against M.tb infection.Comprehensive analysis of the next-generation sequencing results showed that the expression of miR-99a-5p was significantly lower in the MTB infected THP-1 cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE227058 | GEO | 2023/03/12

REPOSITORIES: GEO

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