Transcriptomic analysis reveals the dynamic changes of immune responses during the development of creeping fat in Crohn's disease

ABSTRACT: In Crohn's disease, creeping fat is the characteristic expansion of mesenteric adipose tissue wrapping around the inflamed intestine. Through a comparative transcriptomic analysis of creeping fat and normal-looking mesenteric adipose tissues from patients with Crohn's disease and non-Crohn's disease, we found that a dynamic transcriptional and cell compositional change occurs during the progression from non-Crohn's disease to Crohn's disease, and finally to creeping fat.

ORGANISM(S): Homo sapiens

PROVIDER: GSE227376 | GEO | 2023/09/06

REPOSITORIES: GEO