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Renal tubular Pck1 knockout mice showed albuminuria.

ABSTRACT: We aim to investigate the role of renal Pck1 on albuminuria. To further development of our gene expression approach to biodosimetry, we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to distinguish between wild type mice. To elucidate the molecular mechanisms underlying the increase in albuminuria by our Pck-CKO (Pck1 conditional knockout) mice, we performed DNA microarray analysis using whole kidneys to examine the differences in gene expression between Pck1-CKO and wild-type control mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE228053 | GEO | 2023/03/29

REPOSITORIES: GEO

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