Cell-intrinsic effect of IL-7R signaling of monocytes within C57BL/6J mouse ears infected with Leishmania major [bulk RNA-seq]

ABSTRACT: To determine the cell-intrinsic effect of IL-7R signaling, we sorted il7r-/- (CD45.2+) and WT (CD45.1+) monocytes as internal controls from the same Leishmania major (Lm) infected ears of 50:50 WT:il7r-/ -bone marrow chimera and performed population RNAseq of pools of 50-100 cells per population and infection site using the SMARTseq2 protocol.

ORGANISM(S): Mus musculus

PROVIDER: GSE228456 | GEO | 2026/03/20

REPOSITORIES: GEO