Transcriptomics

Dataset Information

Expression data of lung tissues from ICR mice treated with or without single-walled carbon nanotubes (SWCNTs)


ABSTRACT: The SWCNTs can induce airway hyper-responsiveness (AHR) and chronic obstructive pulmonary disease (COPD)-like changes in mice model. The SWCNTs can induce clusters of proteinases, chemokines/cytokines, and macrophage receptors triggered signaling, which might play critical roles in the SWCNTs-induced pathological changes, including chronic inflammation and tissues remodeling. We used microarrays to detail the global programme of gene expression underlying and identified distinct classes of up-regulated genes during this process.

ORGANISM(S): Mus musculus

PROVIDER: GSE22856 | GEO | 2011/07/09

SECONDARY ACCESSION(S): PRJNA128065

REPOSITORIES: GEO

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