Effect of stimulating PIEZO1 in gastric cancer cells

ABSTRACT: In gastric cancer (GC), PIEZO1 was suggested to promote cell migration by interacting with Trefoil factor family 1 (TFF1) and serve as a therapeutic target against invasion and metastasis. In addition, PIEZO1 demonstrates abundant expression in most GC cell lines and primary samples and highly-expressed PIEZO1 is associated with poor disease-specific survival. As Yoda1 is known to be an agonist of PIEZO1, we try to explore the PIEZO1 function in GC by Yoda1 treatment.

ORGANISM(S): Homo sapiens

PROVIDER: GSE228691 | GEO | 2023/12/08

REPOSITORIES: GEO