PD-1-PD-L1 Axis Activation Suppresses CD8+ T Cells and Improves Nephritis [scRNA-seq, scTCR-seq]

ABSTRACT: To dissect whether PD-1+CD8+ T cells are exhausted in lupus nephritis, scRNA-seq were performed to define the heterogeneous and pathologic subset.

ORGANISM(S): Mus musculus

PROVIDER: GSE228812 | GEO | 2023/04/18

REPOSITORIES: GEO