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Evaluating The Infinium Human MethylationEPIC v2 BeadChip

ABSTRACT: We conducted a comprehensive evaluation of the updated Infinium MethylationEPIC v2 BeadChip (EPICv2). Our evaluation revealed that EPICv2 offers significant improvements over its predecessors, including expanded enhancer coverage, applicability to diverse ancestry groups, support for low-input DNA down to one nanogram, coverage of existing epigenetic clocks, cell type deconvolution panels, and human trait associations, while maintaining accuracy and reproducibility.

ORGANISM(S): Homo sapiens

PROVIDER: GSE228820 | GEO | 2023/07/04

REPOSITORIES: GEO

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