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The cellular landscape of the healthy human intervertebral disc: identification of new immature cell populations and their relationship with mature populations at single cell resolution

ABSTRACT: For this study, we applied scRNA-seq to cells from surgically separated annulus fibrosus and nucleus pulposus tissues to identify A) thecellular landscapes of healthytissues, and B) characterize in detail the composition andgene regulatory networksof immature cell populations.

ORGANISM(S): Homo sapiens

PROVIDER: GSE229711 | GEO | 2024/04/05

REPOSITORIES: GEO

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Sox9 Deletion Causes Severe Intervertebral Disc Degeneration Characterized by Apoptosis, Matrix Remodeling, and Compartment-Specific Transcriptomic Changes

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