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Epigenome analysis of normal skin and hypertrophic scar samples

ABSTRACT: Hypertrophic scarring (HS) is characterized by excessive extracellular matrix deposition, matrix metalloprotein gene activation, and fibroblast invasive growth. However, the methylation level of hypertrophic scarring is poorly understood. Genome wide DNA methylation profiling of normal skin and hypertrophic scar. The Illumina Infinium Methylation EPIC BeadChip (850K) was used to obtain DNA methylation profiles across approximately 853,307 CpGs in liquid based scar samples. Samples included 6 normal skin, and 6 hypertrophic scar.

ORGANISM(S): Homo sapiens

PROVIDER: GSE229848 | GEO | 2023/04/20

REPOSITORIES: GEO

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