The PRAK-NRF2 axis promotes the differentiation of Th17 cells by mediating the redox homeostasis and glycolysis

ABSTRACT: To investigate the function of PRAK in the regulation of Th17 differentiation, we polarized wild type and PRAK-KO naïve CD4+ T cells into Th17 cells for 72h in vitro. We then collected two types of polarized Th17 cells and performed gene expression profiling analysis using data obtained from RNA-seq.

ORGANISM(S): Mus musculus

PROVIDER: GSE229887 | GEO | 2023/04/19

REPOSITORIES: GEO