Genomics

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Nuclear matrix associated protein SMAR1 attenuated acute graft-versus-host disease by targeting JAK-STAT signaling in CD4+ T cells [ATAC-Seq]


ABSTRACT: As a chromatin remodeling factor, SMAR1 might promote local chromatin changes, leading to the activation or inhibition of specific gene subsets in T cells. We performed high-resolution ATAC-seq on primary CD4+ T cells with SMAR1 overexpression (OE) and control (Ctrl), conducting a genome-wide analysis to map the locations and profile the accessibility of diverse regulatory elements.

ORGANISM(S): Homo sapiens

PROVIDER: GSE229932 | GEO | 2025/04/06

REPOSITORIES: GEO

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