Transcriptome of isolated mouse peritoneal endothelial cells

ABSTRACT: To characterize the metabolic profile of peritoneal endothelial cells (ECs) in response to peritoneal dialysis (PD), we performed RNA sequencing of peritoneal ECs isolated from mice treated with PD fluid for 6 weeks (n = 3) and from mice treated with saline for 6 weeks (n = 3). We demonstrated that peritoneal ECs had a hyperglycolytic metabolism in response to PD fluid treatment, which is associated with the development of microvascular alterations and peritoneal dysfunction.

ORGANISM(S): Mus musculus

PROVIDER: GSE230008 | GEO | 2023/12/06

REPOSITORIES: GEO