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Gene expression profile at single cell level of cells isolated from the bone fracture gap and un-injured bone marrow in mouse osteotomy models

ABSTRACT: We investigated the cell composition in the bone fracture (osteotomy) gap under two different ambulatory loading conditions (stiif vs. compliant - external fixator). In addition, we applied an receptor inhibitor or respective isotype control to understand the role of a specific progenitor subpopulation during the onset of bone fracture repair. Un-injured bone marrow was used as control. Some samples were combined prior to library prep as indicated in the sample titles

ORGANISM(S): Mus musculus

PROVIDER: GSE230260 | GEO | 2025/02/14

REPOSITORIES: GEO

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