Mouse ear tissue at 21 days post immunization

ABSTRACT: Gene expression analysis using nCounter immunology panel for profiling among naïve controls and immunized treatment samples. We explored the interplay between type-I IFNs and the development of host protective Th1 immunity in mice immunized with LmCen-/- parasites and challenged with L. donovani parasites and show that downregulation of IRF7 mediated production of IFN-α/β is critical for the induction of protective immunity.

ORGANISM(S): Mus musculus

PROVIDER: GSE230927 | GEO | 2023/04/29

REPOSITORIES: GEO