Transcriptomic Analyses of Ovarian Clear-Cell Carcinoma with Concurrent Endometriosis

ABSTRACT: Endometriosis, a benign inflammatory disease whereby endometrial-like tissue grows outside the uterus, is a risk factor for endometriosis-associated ovarian cancers. In particular, ovarian endometriomas, cystic lesions of deeply invasive endometriosis, are considered the precursor lesion for ovarian clear-cell carcinoma (OCCC). To explore the transcriptomic landscape, OCCC from women with pathology-proven concurrent endometriosis (n = 4) were compared to benign endometriomas (n = 4) by bulk RNA and small-RNA sequencing.

ORGANISM(S): Homo sapiens

PROVIDER: GSE230956 | GEO | 2023/07/29

REPOSITORIES: GEO