Specific stroke-induced miRNAs could mediate and interaction between peripheral blood and the brain

ABSTRACT: Ischemic stroke is a major public health problem that is currently among the top leading causes of serious, long-term disability worldwide. The lack of effective treatment strategies prompted a search for new molecular targets for stroke prognosis and therapy. One of the epigenetic mechanisms controlling stroke progression and recovery involves signaling pathways mediated by short non-coding RNAs called microRNAs (miRNAs). Recent studies demonstrated stroke-specific changes in miRNA expression. The main goal of the present study was identify miRNAs mediating a communication between the brain and peripheral circulation in human stroke.

ORGANISM(S): Homo sapiens

PROVIDER: GSE231431 | GEO | 2023/05/31

REPOSITORIES: GEO