African swine fever infection epigenetically regulate host membrane protein-encoding genes

ABSTRACT: African swine fever virus (ASFV) is a highly contagious pathogen that primarily affects domestic and wild pigs with specific tropism to porcine alveolar macrophages (PAMs). However, the host receptors involved in ASFV infection remain unknow. Here, we present a multi-omic epigenetic atlas of ASFV-exposed PAMs and profile 3D chromatin architecture and single-nucleus chromatin accessibility landscapes (sn-ATAC)

ORGANISM(S): Sus scrofa

PROVIDER: GSE231435 | GEO | 2025/04/18

REPOSITORIES: GEO