Macrophage containing multicellular lung organoids [bulkRNA-seq]

ABSTRACT: Proper lung development and function maintenance depend on the cross-talk between resident immune cell populations and lung epithelial cells. However, understanding the underlying cellular and molecular mechanisms are difficult to study in human. Here, we present a method to develop macrophage-containing alveolar organoids from human pluripotent stem cells to investigate reciprocal interactions between alveolar macrophages and epithelial cells in lung development.

ORGANISM(S): Homo sapiens

PROVIDER: GSE231466 | GEO | 2024/07/07

REPOSITORIES: GEO