Genomics

Dataset Information

0

Directional endothelial communication by polarized extracellular vesicle release


ABSTRACT: EVs were isolated from primary human aortic endothelial cells (ECs) (+/- IL-1b activation), quantified, and analysed by miRNA transcriptomics and proteomics. Compared to quiescent ECs, activated ECs increased EV release, with miRNA and protein cargo that were related to atherosclerosis pathways. RNA sequencing of EV-treated monocytes and vascular smooth muscle cells (VSMCs) revealed that EVs from activated ECs altered pathways that were pro-inflammatory and atherogenic.

ORGANISM(S): Homo sapiens

PROVIDER: GSE231715 | GEO | 2024/01/02

REPOSITORIES: GEO

Similar Datasets

2024-01-02 | GSE230246 | GEO
2024-01-02 | GSE230289 | GEO
2016-10-05 | E-MTAB-4560 | biostudies-arrayexpress
2022-02-15 | E-MTAB-11417 | biostudies-arrayexpress
2015-05-07 | E-GEOD-59958 | biostudies-arrayexpress
2016-02-09 | E-GEOD-74879 | biostudies-arrayexpress
2022-03-23 | GSE199035 | GEO
2013-06-19 | E-GEOD-47897 | biostudies-arrayexpress
2022-02-02 | GSE195931 | GEO
2020-05-12 | GSE132161 | GEO