ARIH1 activates STING-mediated T-cell activation and sensitizes tumors to immune checkpoint blockade

ABSTRACT: To explore the molecular mechanisms how ARIH1 activates CD8+ T cells and enhances PD-L1 blockade therapy, we performed RNA sequencing (RNA-seq) to determine whether Arih1 overexpression affects the gene expression in 4T1 cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE231726 | GEO | 2023/06/02

REPOSITORIES: GEO