Differences in gene expression of liver cancer cells after co-culture with activated CD8+ T cells in vitro

ABSTRACT: To investigate the difference in gene expression of liver cancer cells after co-culture with activated CD8+T cells , we established a tumor cells/activated CD8+T cells co-culture system in which murine liver cancer cell line hepa1-6 were co-cultured and attacked directly by murine in vitro activated spleen naive CD8+T cells (effector: target=5:1) for 48 hours. We then performed gene expression profiling analysis using data obtained from RNA-seq of two different groups (immune attacked or control) with 5 repetitions per group.

ORGANISM(S): Mus musculus

PROVIDER: GSE232024 | GEO | 2024/07/25

REPOSITORIES: GEO