Study Nocte's functions in transcription and translation in Drosophila eye discs

ABSTRACT: Nocte is an RNA binding protein but its functions in Drosophila eye development is unknown. We found that knockdown of nocte by RNAi in Drosophila eyes leads to small and rough eye phenotypes. We detected nocte's functions at mRNA levels by doing RNA-seq with purified polyA mRNA. We detected nocte's functions in mRNA translation by doing Ribo-seq and total RNA-seq to calculate the translation efficiencies.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE232395 | GEO | 2023/11/10

REPOSITORIES: GEO