RNA-seq of mouse tissue samples from animal model : Effects of AREG on gene expression

ABSTRACT: In the present study, RNA-seq technique were performed to explore biological significance of AREG in the neuro-cutaneous signaling network of chronic itch. At least f repetitive mRNAs were deeply sequenced using MGISEQ-2000 to generate an mRNA profiles. In high-throughput sequencing of tissue samples using protein and control solvent intradermal injection, we found that increased intradermal AREG affected the expression of multiple pruritus and skin inflammatory factors associated with human chronic dermatitis dermatitis dermatitis dermatitis dermatitis dermatitis dermatitis. These changes may indicate that AREG is closely related to inflammation and pruritus. This finding might help us to better understand the immune-neuro-modulatory mechanism in itch circuits.

ORGANISM(S): Mus musculus

PROVIDER: GSE232421 | GEO | 2026/09/24

REPOSITORIES: GEO