Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Distinct and overlapping immunological responses to SARS-CoV-2 and Mycobacterium tuberculosis identified by single-cell RNA-seq of co-infected whole blood

ABSTRACT: To determine distinct and similar aspects of the human immune responses in the blood to Mycobacterium tuberculosis and SARS-CoV-2 infection or concurrent infection with both pathogens.

ORGANISM(S): Homo sapiens

PROVIDER: GSE232705 | GEO | 2025/07/05

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Mycobacterium tuberculosis and macrophage response

Project description:This SuperSeries is composed of the following subset Series: GSE6209: The global transcriptional profile of Mycobacterium tuberculosis during human macrophages infection GSE7962: Sigma factor E of Mycobacterium tuberculosis controls the expression of bacterial components that modulate macrophages Keywords: SuperSeries Refer to individual Series

2010-05-25 | E-GEOD-7963 | biostudies-arrayexpress

A novel copper-responsive regulon in Mycobacterium tuberculosis.

Project description:In this study, we report the identification of a five-locus copper-inducible regulon in Mycobacterium tuberculosis. The identification of a copper responsive regulon unique to pathogenic Mycobacteria suggests copper homeostasis must be maintained during an infection.

2010-10-27 | GSE23498 | GEO

Gene expression data from THP-1 cells infected with different Mycobacterium tuberculosis strains

Project description:Host-pathogen interactions in Mycobacterium tuberculosis infection still remain poorly understood. We investigated the host immune response to different reference Mycobacterium tuberculosis strains in THP-1 cells. Major differences in the gene expression profiles were identified in response to infection with these strains. These findings shed new insights into the dynamic variation in tuberculosis immune response and pathogenesis. We used Affymetrix GeneChip Human Exon 1.0 ST microarrays to investigate host differential gene expression in response to different Mycobacterium tuberculosis strains.

2024-10-24 | GSE246736 | GEO

Genome-wide analysis of mesenchymal stem cell gene expression upon Mycobacterium tuberculosis infection

Project description:Analysis of mesenchymal stell cell gene expression level upon Mycobacterium tuberculosis infection. Transcriptome landscape provide important information of the response of stem cell infetion with Mycobacterium tuberculosis such as antibacterial pathways and specific anabolic/catabolic cellular functions.

2020-01-01 | GSE133803 | GEO

Distinct and overlapping immunological responses to SARS-CoV-2 and Mycobacterium tuberculosis identified by single-cell RNA-seq of co-infected whole blood

Project description:Distinct and overlapping immunological responses to SARS-CoV-2 and Mycobacterium tuberculosis identified by single-cell RNA-seq of co-infected whole blood

| PRJNA973610 | ENA

Comparative Transcriptome of cattle PBMCs post Mycobacterium tuberculosis infection

Project description:This comparative transcriptomic study examines the differences in the gene expression profile in PBMCs from indigenous Sahiwal and Crossbred (Sahiwal x Holstein Friesian) cattle in response to Infection with virulent Mycobacterium tuberculosis and vaccine stain M. bovis BCG.

2025-03-03 | GSE277021 | GEO

Mycobacterium tuberculosis cording in lymphatic endothelial cells (hLEC)

Project description:Mycobacterium tuberculosis (Mtb) displayed cording phenotypes during intracellular infection. RNA-Seq was used to identify transcriptional programmes expressed by hLEC that actviates pathways relating to cellular pro-survival and cyosolic surveillance of intracellular Mtb. Mtb cording was found to be a mechanism to evade xenophagy in the cytosol of endothelial cells.

2020-06-04 | GSE110564 | GEO

Mycobacterium tuberculosis whiB4 mutant expression

Project description:Comparison of gene expression profile of the whiB4 mutant strain of Mycobacterium tuberculosis with the wild type Mycobacterium tuberculosis H37RV Mtb WhiB4 mutant mRNA was compared with the mRNA of wtMtb H37RV under aerobic conditons

2012-07-24 | GSE37840 | GEO

Genome-wide analysis of gene expression in lung cells from metformin treated Mycobacterium tuberculosis infected mice

Project description:Analysis of Metfromin induced changes in the lung cells of Mycobacterium tuberculosis infected mouse at gene expression level. The hypothesis tested in the present study was whether metformin has any effect on the host immune response in Mycobacterium tuberculosis infected mice? Results provide important information on the effect of metformin on the inflammatory response and immune activation associated with mycobacterial infection. In conclusion, Metfromin normalizes the chronic inflammation associated with Mycobacterium tuberculosis infection.

2014-12-02 | GSE57275 | GEO

mRNA degradation in Mycobacterium tuberculosis

Project description:This SuperSeries is composed of the following subset Series: GSE36341: mRNA degradation in Mycobacterium tuberculosis under aerobic conditions GSE36342: mRNA degradation in Mycobacterium smegmatis under aerobic conditions GSE36343: mRNA degradation in Mycobacterium tuberculosis during cold and hypoxic stress GSE36344: mRNA degradation in Mycobacterium tuberculosis with DosR ectopically induced Refer to individual Series

2012-03-08 | E-GEOD-36345 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data