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Single-cell transcriptomics reveal the dynamic of cancer stem-like cells during cholangiocarcinoma progression

ABSTRACT: We investigated YAP/AKT hydrodynamic tail vein injected murine models and we analyzed the correlative change of immune cell profile and stemness during cholangiocarcinoma progression using single-cell RNA sequencing

ORGANISM(S): Mus musculus

PROVIDER: GSE233623 | GEO | 2023/12/01

REPOSITORIES: GEO

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Anti-cancer activity of verteporfin in cholangiocarcinoma

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Project description:To investigate the mechanism by which YAP regulates methionine metabolism, seven-week-old C57 mice were injected with AAV8-TBG-control or AAV8-TBG-YAP-S127A through tail vein. 8 weeks later, the primary hepatocytes from two groups were isolated for RNA sequence analysis.

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Effect of YAP overexpression on HuCCT1 cholangiocarcinoma cell line transcriptome (YAPS94A)

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Effect of YAP overexpression on HuCCT1 cholangiocarcinoma cell line transcriptome (YAP overexpression)

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Promotion of Cholangiocarcinoma Growth by Diverse Cancer-associated Fibroblast Subpopulations

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