Amyloid precursor protein (APP) regulates gliogenesis and 2 neurogenesis of human neural stem cells by several signaling 3 pathways

ABSTRACT: we have evaluated the effects of APP overexpression in hNSCs at a global 16 level by a transcriptomic analysis using the massive RNA sequencing (RNA-seq) technology. Spe-17 cifically, we have focused on differentially expressed genes that are related to neuronal and glial 18 differentiation processes, as well as on groups of differentially expressed genes associated with dif-19 ferent signaling pathways, in order to find a possible interaction between them and APP

ORGANISM(S): Homo sapiens

PROVIDER: GSE233651 | GEO | 2023/07/31

REPOSITORIES: GEO