Network analysis reveals strain-dependent response to misfolded tau aggregates (NanoString)

ABSTRACT: To investigate the effect of wild-derived genetic background on modeling tau aggregation, we injected either AAV-eGFP or AAV-hTauP301L into postnatal day 0 mice to drive widespread expression. We then performed gene expression profiling analysis using data obtained from Nanostring nCounter Mouse Neuroinflammation Panel from mouse brain cortex of 6 month old hTauP301L- or eGFP-mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE233988 | GEO | 2023/07/25

REPOSITORIES: GEO