Genomics

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NAD(H) homeostasis is essential for host protection mediated by glycolytic myeloid cells in tuberculosis


ABSTRACT: To investigate the role of LDHA in myeloid cells in the response to pulmonary infection with Mycobacterium tuberculosis, we infected LDHAfl/fl:LysM+/- mice with Mtb-H37Rv via the aerosol route. We then performed gene expression profiling analysis using data obtained from RNA-seq of the lungs of these animals at 4 and 30 weeks post infection.

ORGANISM(S): Mus musculus

PROVIDER: GSE234115 | GEO | 2023/08/09

REPOSITORIES: GEO

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