Massively Parallel Binding Assay (MPBA) reveals limited transcription factor cooperation, challenging models of specificity

ABSTRACT: We provide the data collected using the method MPBA, allowing parallel measurement of TF binding to thousands of DNA sequence-variants within cells. The method was applied to quantify binding of dozens of transcription factors (TFs) to libraries of mutated regulatory regions, systematically screening all motif combinations.

ORGANISM(S): Saccharomyces cerevisiae

PROVIDER: GSE234455 | GEO | 2024/06/26

REPOSITORIES: GEO