Transcriptomics

Dataset Information

0

Transcriptomic analysis of dynamic dysregulation in brainstem autonomic nuclei during the development of hypertension


ABSTRACT: Neurogenic hypertension stems from an imbalance in autonomic function that shifts the central cardiovascular control circuits towards a state of dysfunction. Using the female spontaneously hypertensive rat (SHR) and the normotensive Wistar Kyoto (WKY) rat model, we compared the transcriptomic changes in three autonomic nuclei in the brainstem, the nucleus of the solitary tract (NTS), caudal ventrolateral medulla (CVLM), and rostral ventrolateral medulla (RVLM) in a time series at 8, 10, 12, 16, and 24 weeks of age, spanning the pre-hypertensive stage through extended chronic hypertension.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE234784 | GEO | 2024/01/30

REPOSITORIES: GEO

Dataset's files

Source:
Action DRS
Other
Items per page:
1 - 1 of 1

Similar Datasets

| PRJNA1139741 | ENA
2008-12-31 | GSE10366 | GEO
2023-09-14 | GSE235234 | GEO
2010-12-18 | E-GEOD-26138 | biostudies-arrayexpress
| PRJNA983212 | ENA
2016-10-12 | GSE87746 | GEO
2021-12-14 | MSV000088563 | MassIVE
2022-12-07 | GSE220296 | GEO
2020-09-24 | PXD021210 | Pride
2016-12-07 | GSE90956 | GEO