Whole-exome sequencing reveals mutational signature of hypertrophic cardiomyopathy

ABSTRACT: Hypertrophic cardiomyopathy (HCM) is an extremely insidious, lethal disease caused by genetic variation and characterized by cardiac hypertrophy. It has been studied for nearly 70 years since its discovery, but its cause of the disease remains a mystery. Here, aiming to identify pathogenic genes that causes HCM, 14 patients with HCM were collected and whole exome sequencing (WES) of peripheral blood DNA was performed.

ORGANISM(S): Homo sapiens

PROVIDER: GSE234820 | GEO | 2026/06/13

REPOSITORIES: GEO