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A scRNAseq atlas of larval Drosophila ventral cord - a resource for studying motor systems function and development

ABSTRACT: Drosophila larval ventral nerve cord (VNC) shares many similarities with the spinal cord of vertebrates and has emerged as a major model for understanding the development and function of motor systems. We use high quality single cell RNA sequencing to create a comprehensive atlas of larval VNC cell types. Our atlas provides a high-resolution characterization of larval VNC capturing primary neurons, glia and the functional landscape that coordinates larval behavior. At the same time, this atlas offers unique insights into neurogenesis and into the strategies and signaling networks utilized for generation of the adult VNC.

ORGANISM(S): Drosophila melanogaster

PROVIDER: GSE235231 | GEO | 2024/02/14

REPOSITORIES: GEO

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