Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

The Heparin-binding hemagglutinin protein of Mycobacterium tuberculosis is a nucleoid-associated protein

ABSTRACT: Analyzing differences in transcriptome profile of Mto3DhbhA in 7H9 and Sauton's media compared to control Mto3.

ORGANISM(S): Mycobacterium tuberculosis

PROVIDER: GSE235293 | GEO | 2023/11/29

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Transcriptional response of Mycobacterium tuberculosis to cigarette smoke condensate

Project description:Mycbacterium tuberculosis was exposed to cigarette smoke condensate (CSC) in 7H9 dextrose culture media. The transcriptional response to cigarette smoke condensate was compared to that of exposure to the CSC diluent, DMSO..

2021-04-15 | GSE172041 | GEO

A novel copper-responsive regulon in Mycobacterium tuberculosis.

Project description:In this study, we report the identification of a five-locus copper-inducible regulon in Mycobacterium tuberculosis. The identification of a copper responsive regulon unique to pathogenic Mycobacteria suggests copper homeostasis must be maintained during an infection. WT and mutant Mtb cells were grown in Sauton's minimal media to early stationary phase (OD580 = 1.5) and treated with 500 mM copper sulfate (CuSO4) for four hours or the absence

2010-10-27 | E-GEOD-23498 | biostudies-arrayexpress

Targeting of Mycobacterium tuberculosis heparin-binding hemagglutinin to mitochondria in macrophages.

Project description: Not available

| S-EPMC3234249 | biostudies-literature

Transcriptional Response of Mycobacterium tuberculosis H37Rv to Ca2+

Project description:To understand the response of M. tuberculosis (MTB) to Ca2+, we performed transcriptomics on MTB bacilli grown in chelex treated Sauton's medium with or without 1mM Ca2+ .

2022-11-07 | GSE214266 | GEO

Transcriptomics of Zinc-limited and Zinc-replete Mycobacterium tuberculosis

Project description:Mycobacterium tuberculosis H37Rv (Mtb) was grown in Sauton's medium with and without added zinc. Cultures were grown for 10 days and RNA was harvested from TRIzol extractions.

2021-04-21 | GSE168513 | GEO

Mycobacterium tuberculosis ESX-3 conditional mutant expression

Project description:Transcriptional profile of esx-3 conditional mutant strain (TB79) vs its parental strain (TB38) grown in 7H9 in presence of 100ng/ml Atc for 48h

2013-06-12 | GSE47834 | GEO

RNA-sequencing of Mycobacterium tuberculosis treated with C10

Project description:We sought to identify pathways dysregulated in Mycobacterium tuberculosis upon treatment with the compound C10. We treated M. tuberculosis with DMSO, 5 μM C10, or 25 μM C10 for 48 hours in Sauton's medium and used RNA-sequencing to compare transcriptional profiles.

2019-05-31 | GSE129833 | GEO

Transcriptional profiling of Mycobacterium tuberculosis H37Rv in whole blood from HIV- and HIV+ individuals

Project description:Mycobacterium tuberculosis (M. tb), the cause of tuberculosis (TB), utilizes the blood circulation to spread systemically and establish infection, and the risk of developing active TB (pulmonary and extrapulmonary) is significantly increased in individuals infected with human immunodeficiency virus (HIV). In this work, we have used DNA microarray analysis to investigate the transcriptome of M. tb replicating in human whole blood from both HIV-negative and HIV-positive donors compared to M. tb grown in Middlebrook 7H9 broth media in order to identify M. tb adaptations to this host environment as well as M. tb mechanisms/factors contributing to increased active and disseminated TB during M. tb/HIV co-infection. We compared the global gene expression of M. tb H37Rv replicating in whole blood from 6 HIV- and 6 HIV+ individulas at 96 hr to M. tb grown to log phase in Middlebrook 7H9 media.

2014-03-31 | E-GEOD-49760 | biostudies-arrayexpress

Virulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein.

Project description: Not available

| S-EPMC3315491 | biostudies-literature

Basal in vitro transcriptomes of Mycobacterium tuberculosis complex (MTC) clinical isolates

Project description:This study uses microarray analyses to examine baseline gene expression profiles for Mycobacterium tuberculosis complex clinical isolates relative to reference strain CDC1551 during log phase growth in vitro in 7H9 broth. For this in vitro analyses, log-phase mycobacteria in starter cultures grown to mid-log from frozen stocks were inoculated into 7H9-OADC medium in 25-cm2 vented flasks at an OD of ~0.05 and grown without shaking for ~1 week to an OD of ~0.5-0.6.

2010-07-09 | GSE21111 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data