Alterations in lysosomal gene expression and lipid homeostasis in patient-derived liver organoids with acid sphingomyelinase deficiency

ABSTRACT: We generated hepatic organoids from Nieman Pick Type B patients with the aim to investigate their lipid status. To discover genes related to lipid metabolism likely involved in lipid deposits.

ORGANISM(S): Homo sapiens

PROVIDER: GSE236213 | GEO | 2023/07/04

REPOSITORIES: GEO