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Genetic and Environmental interactions contribute to immune variation in rewilded mice

ABSTRACT: The relative and synergistic contributions of genetics and environment to inter-individual immune response variation remain unclear, despite its implications for understanding both evolutionary biology and medicine. We used single cell RNA sequencing (scRNA-seq) to quantify the interactive effects of genotype and environment on immune traits by investigating three inbred mouse sttrain rewilded in an outdoor enclosure and infected with the parasite, Trichuris muris

ORGANISM(S): Mus musculus

PROVIDER: GSE236347 | GEO | 2024/04/29

REPOSITORIES: GEO

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Laboratory mice housed in the natural environment identifies genetic and environmental contributions to immune variation

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