SMAD4 regulates the progression of cholangiocarcinoma (CCA) by modulating the expression of STING1

ABSTRACT: SMAD4 regulates the expression of STING1 through its transcription regulating function. Dual low expression of STING1 and SMAD4 had more power in predicting patient survival. These results indicate that SMAD4-silenced CCA may downregulate its STING1 expression to adapt to the immune system.

ORGANISM(S): Homo sapiens

PROVIDER: GSE236894 | GEO | 2025/09/30

REPOSITORIES: GEO