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RNA-seq analysis of Lrig1+ and Lrig1- CD4+ T cells in mouse spleen

ABSTRACT: Regulatory T cell (Treg) is the immune-suppressive T cell subset and the crucial component for preventing autoimmunity. The molecules defining the suppressive population of T cells phenotypically and functionally remain to be discovered. In this study, we report that Lrig1 is highly expressed in suppressive CD4+ T cell populations. We performed RNA-seq analysis of CD4+Lrig1+ and CD4+Lrig1- T cells from mouse splenocytes to analyze the genes involeved in the suppressive function of T cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE236988 | GEO | 2023/07/16

REPOSITORIES: GEO

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