Genomics

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Gene expression profiling on bronchoalveolar lavage (BAL) cells treated with all-trans-retinoic acid (ATRA)


ABSTRACT: All-trans retinoic acid (ATRA) is a potent retinoid, which has been used successfully in different clinical settings as a potential drug to treat COPD and emphysema. In alveolar macrophages, ATRA selectively down-regulates MMP-9 and up-regulates TIMP-1 expression. In the present study, we analyzed additional genes modulated by ATRA by performing mRNA expression array on alveolar macrophages after treatment with ATRA.

ORGANISM(S): Homo sapiens

PROVIDER: GSE23704 | GEO | 2010/09/04

SECONDARY ACCESSION(S): PRJNA130901

REPOSITORIES: GEO

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