The effect of pressure on gene expression of blood and venous endothelial cells in humans

ABSTRACT: Two matched groups of Heart Failure with reduced ejection fraction patients with no peripheral venous congestion were studied: with recent prior heart failure hospitalization vs. without recent heart failure hospitalization. Peripheral venous congestion was modeled by inflating a cuff around the dominant arm, targeting an ~30mmHg increase in venous pressure (venous stress test). Blood and endothelial cells were sampled before and after 90 minutes of venous stress test.

ORGANISM(S): Homo sapiens

PROVIDER: GSE237856 | GEO | 2023/08/28

REPOSITORIES: GEO