Hepatic T-cell senescence is implicated in the progression of fatty liver disease in patients with type 2 diabetes

ABSTRACT: Immunosenescence and exhaustion are involved in the development and progression of type 2 diabetes (T2D) and metabolic liver diseases, including fatty liver, fibrosis, and cirrhosis, in humans. However, the relationships of the senescence and exhaustion of T cells with insulin resistance-associated liver diseases remain incompletely understood. To better define the relationship of T2D with nonalcoholic fatty liver disease, 59 patients with T2D were studied.

ORGANISM(S): Mus musculus

PROVIDER: GSE239612 | GEO | 2023/08/05

REPOSITORIES: GEO