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Role of EGR1 in vasculogenic mimicry of MDA-MB-231 cells

ABSTRACT: Vasculogenic mimicry (VM) is an intriguing phenomenon observed in tumor masses, in which cancer cells organize themselves into capillary-like channels that closely resemble the structure and function of blood vessels. Although VM is believed to contribute to alternative tumor vascularization, the detailed regulatory mechanisms controlling these cellular processes remain poorly understood. Our study aimed to investigate the role of Early Growth Response 1 (EGR1) in regulating VM in aggressive cancer cells, specifically MDA-MB-231 triple-negative breast cancer cells.

ORGANISM(S): Homo sapiens

PROVIDER: GSE240489 | GEO | 2023/08/15

REPOSITORIES: GEO

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