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Transcriptional profile of Candida albicans during Hypoxic conditions.

ABSTRACT: Whole genome microarray were used to generate the transcriptional profile of C.albicans in hypoxic condition.

ORGANISM(S): Candida albicans

PROVIDER: GSE24073 | GEO | 2010/11/15

SECONDARY ACCESSION(S): PRJNA133659

REPOSITORIES: GEO

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Transcriptional profile of Candida albicans during Hypoxic conditions.

Project description:Whole genome microarray were used to generate the transcriptional profile of C.albicans in hypoxic condition. RNA was isolated from DAY286 grown in YPD medium in normoxia or hypoxia at 30 degree Celsius for 3.5 h, and labeled with Cy3 or Cy5. Eight independent biological replicates were compared. 2 dye swaps were perfomed so that 6 out of 8 samples isolated from normoxic culture were labeled with Cy3, and 2 were labeled with Cy5.

2010-11-15 | E-GEOD-24073 | biostudies-arrayexpress

Transcriptional profile of Candida albicans DAY286 versus UPC2 delete, both at 1% oxygen (hypoxia).

Project description:Whole genome microarray were used to generate the transcriptional profile of C.albicans UPC2 delete in hypoxia.

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Transcriptional profile of Candida albicans DAY286 versus UPC2 delete, both at 1% oxygen (hypoxia).

Project description:Whole genome microarray were used to generate the transcriptional profile of C.albicans UPC2 delete in hypoxia. RNA was isolated from DAY286 or UPC2 delete grown in YPD medium in hypoxia at 30 degree Celsius for 3.5 h, and labeled with Cy3 or Cy5. Nine independent biological replicates were compared. 3 dye swaps were perfomed so that 6 out of 9 samples isolated from DAY286 in hypoxic culture were labeled with Cy3, and 3 were labeled with Cy5.

2010-11-15 | E-GEOD-24075 | biostudies-arrayexpress

Transcriptional profile of Candida albicans DAY286 culture without ketoconazole versus DAY286 culture with 0.04 μg/ml ketoconazole, both at 20% oxygen (normoxia).

Project description:Whole genome microarray were used to generate the transcriptional profile of C.albicans in the presence of ketoconazole.

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Transcriptional profile of Candida parapsilosis CLIB214 21% Oxygen (normoxia) versus at 1% oxygen (hypoxia).

Project description:Whole genome microarray were used to generate the transcriptional profile of C. parapsilosis in hypoxic condition.

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Natural variation in phenotypic impact of Candida albicans cyclin gene HGC1

Project description:Purpose: Studying the role of HGC1 in the strain variation among the clinical isolates of C.albicans

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Comparative genomics of ten clinical Candida albicans strains

Project description:Candida albicans is the most common fungal pathogen in humans. C.albicans tolerates aneuploidy of all of its chromosomes. Genome plasticity is a hallmark of C.albicans. It is an adaptation strategy of this species. But questions like the extent of such genomic variability, which genes contribute to the divergence, and what mechanisms drive the adaptive genetic change, are not well answered yet. We used array-based comparative genomic hybridization (array CGH) to investigate the diversity of gene contents of 10 clinical C.albicans strains, of various anatomical origins and genotypes. One self to self hybridization was included as a control.

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Transcriptional profile of Candida parapsilosis CLIB214 21% Oxygen (normoxia) versus at 1% oxygen (hypoxia).

Project description:Whole genome microarray were used to generate the transcriptional profile of C. parapsilosis in hypoxic condition. RNA was isolated from CLIB214 grown in YPD medium in normoxia or hypoxia at 30 degree Celsius for 3.5 h, and labeled with Cy3 or Cy5. Four independent biological replicates were compared. Isolates from normoxic condition were labeled with Cy3 and isolates from hypoxic condition were labeled with Cy5.

2011-11-30 | E-GEOD-32712 | biostudies-arrayexpress

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