Mechanical Ventilation Augments LPS-induced Lung Injury

ABSTRACT: This experiment investigated the role of mechanical ventilation (MV) in modulating lung's transcriptional response to LPS. Twenty four C57/B6 male mice were randomized to four groups: 1. Control, 2. MV, 3. LPS and 4. MV+LPS. Expression profiling of whole lungs revealed a significant augmentation of the transcriptional response in the combined MV+LPS group relative to the other 3 conditions. Keywords: repeat sample

ORGANISM(S): Mus musculus

PROVIDER: GSE2411 | GEO | 2005/08/01

SECONDARY ACCESSION(S): PRJNA91623

REPOSITORIES: GEO